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目的:观察氯吡格雷加丹红注射液治疗不稳定型心绞痛的临床疗效。方法:选择不稳定型心绞痛180例,随机分为观察组和对照组各90例。两组均给予硝酸酯类药物、阿司匹林、β受体阻滞药、钙离子拮抗药等常规治疗。对照组采用口服氯吡格雷治疗,每次75mg,每天1次;观察组在对照组基础上,加用丹红注射液20ml,加入到5%葡萄糖或生理盐水250ml中,静脉滴注,每天1次。两组均治疗14天。观察治疗后两组心绞痛发作次数、心电图变化等。结果:观察组心绞痛改善81例(90.0%),对照组67例(74.4%),两组比较差异显著(P<0.05)。观察组心电图改善77例(85.6%),对照组66例(68.9%),两组比较差异显著(P<0.05)。结论:氯吡格雷加丹红注射液治疗不稳定型心绞痛疗效好。
Objective: To observe the clinical effect of clopidogrel plus red injection in the treatment of unstable angina pectoris. Methods: 180 cases of unstable angina were randomly divided into observation group and control group, 90 cases each. Both groups were given nitrates, aspirin, β blockers, calcium antagonists and other conventional treatment. The control group was treated with oral clopidogrel, 75mg once daily. The observation group was added with 20ml of Danhong injection on the basis of the control group, added to 250ml of 5% dextrose or normal saline, intravenously 1 Times. Both groups were treated for 14 days. After treatment, angina pectoris episodes and ECG changes were observed in both groups. Results: 81 cases (90.0%) improved angina in the observation group and 67 cases (74.4%) in the control group, with significant difference between the two groups (P <0.05). There were 77 cases (85.6%) in the observation group and 66 cases (68.9%) in the control group, with significant difference between the two groups (P <0.05). Conclusion: Clopidogrel plus red injection is effective in treating unstable angina pectoris.