本文用小鼠抬脚法对文献记载的青霉素无痛配伍方法进行了评定,同时对局麻药的止痛效果进行了观察。结果表明,文献记载的配伍方法只有在一定条件下可见止痛作用,但不能根本解除青霉素注射时的疼痛。在所筛选的几种局麻药中利多卡因及丁吡卡因的止痛效果较为满意。本文的实验数据可为临床应用提供参考。 In this paper, the method of mouse bearing foot penicillin painless compatibility method was assessed, while analgesic effect of local anesthetics were observed. The results showed that the compatibility of the literature documented only under certain conditions analgesic effect, but can not be completely relieved of penicillin injection pain. In the screening of several local anesthetic lidocaine and tetracycline analgesic effect is more satisfactory. The experimental data in this paper can provide a reference for clinical application.