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根据光学原理,提出一种由椭球面反射器和单圆锥辐射器组成的超宽带冲激脉冲辐射天线(IRA),通过IRA将高强度皮秒电场脉冲无创伤地传输至生物组织深处靶点位置形成有效的聚焦,汇聚的皮秒电场脉冲能够诱导肿瘤细胞的细胞器(线粒体)跨膜电位发生变化而崩溃,继而杀死肿瘤细胞,并能避免对正常组织的损伤,从而实现肿瘤的无创治疗。根据时域电磁场理论,对皮秒电场脉冲分别在有和无生物组织情况下的传播特性进行了分析。皮秒电场脉冲在传播过程中都能保持输入脉冲的冲激特性,并且在靶点区域具有很高的分辨率。同时,由于媒质的色散性质,皮秒电场脉冲的幅值会发生衰减,且脉宽出现拓宽现象。
According to the principle of optics, an ultra-wideband impulse pulsed antenna (IRA) consisting of an ellipsoidal reflector and a single cone radiator is proposed to transfer the high-intensity picosecond electric field pulse to the target of biological tissue through the IRA The formation of an effective focus and convergence of the picosecond electric field pulse can induce tumor cell organelles (mitochondria) transmembrane potential changes and collapse, and then kill the tumor cells, and to avoid damage to normal tissues in order to achieve noninvasive treatment of tumors . According to the theory of time-domain electromagnetic field, the propagation characteristics of picosecond electric field pulse with and without biological tissue were analyzed respectively. The picosecond electric field pulse maintains the impulse characteristics of the input pulse during propagation and has a high resolution in the target region. At the same time, due to the dispersive nature of the medium, the amplitude of the picosecond electric field pulse will attenuate and the pulse width will broaden.