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目的通过对来自于寨卡病毒流行区的入境人员进行追踪和筛查,发现寨卡病毒感染者,对其进行隔离,以期防止寨卡病毒病的本地化流行。方法江门恩平市(县)对2016年2月28日至7月15日来自于委内瑞拉、哥斯达黎加等国家的1 141例入境人员进行健康随访,并对725例进行了流行病学调查,并采集血液、唾液或尿液,采用RT-PCR法检测寨卡病毒核酸,筛查出寨卡病毒感染者。结果通过主动追踪和筛查,从725例中查出8例寨卡病毒病患者和3例隐性感染者,检出阳性率为1.52%。其中男性检测423例,阳性4例;女性检测302例,阳性7例,男女感染率相近,差异无统计学意义(χ2=2.22,P>0.05)。73.33%的感染者通过主动监测被检出,开展该项工作4个月来无本地病例出现。结论对寨卡流行区入境人员进行主动追踪和筛查,是防控寨卡病毒病本土化流行的有效措施之一。
Objective To identify and isolate Zika virus-infected individuals by tracking and screening immigrants from the endemic Zika virus area in order to prevent the localization of Zika virus disease. Methods Enping City (county) of Jiangmen conducted a health follow-up visit to 1,141 immigrants from Venezuela, Costa Rica and other countries from February 28 to July 15, 2016, carried out epidemiological investigations on 725 patients and collected blood , Saliva or urine. The Zika virus nucleic acid was detected by RT-PCR and Zika virus was screened out. Results Through active follow-up and screening, 8 cases of Zika virus disease and 3 cases of latent infection were detected in 725 cases. The positive rate was 1.52%. Among them, 423 were male and 4 were positive; 302 were female and 7 were positive. The infection rate was similar between male and female, with no significant difference (χ2 = 2.22, P> 0.05). 73.33% of the infected persons were detected through active surveillance. No local cases were found after 4 months. Conclusion The active follow-up and screening of immigrants in Zika area is one of the effective measures to prevent and control the local epidemic of Zika virus disease.