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目的通过棕榈花蕾水提物对雌性家兔体内激素水平的影响,进一步探讨其抗生育作用机制。方法给健康雌性未孕家兔ip不同剂量的棕榈花蕾水提物,每天1次,连续9d。给药后分别从耳动脉取血,测定血清中的FT3、FT4、雌二醇、孕酮。结果与生理盐水组相比,棕榈花蕾水提物高剂量组明显降低家兔血清中FT3水平、升高孕酮含量,而各剂量组对FT4和雌二醇含量无明显影响。结论棕榈花蕾水提物能降低家兔血清中FT3水平,并升高孕酮含量。
Objective To study the effect of palm bud flower water extract on the hormone levels in female rabbits to further explore its anti-fertility mechanism. Methods Healthy pregnant female rabbits ip different doses of palm flower bud water extract once a day for 9 days. Blood was collected from the ear artery after administration, and the serum FT3, FT4, estradiol and progesterone were measured. Results Compared with the saline group, the high-dose palm-flower bud water extract significantly reduced the level of FT3 in serum and increased the content of progesterone in rabbits, but no significant effect on FT4 and estradiol content was observed in each dose group. Conclusion Palm bud water extract can reduce the level of FT3 in rabbit serum and increase the content of progesterone.