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由人类免疫缺陷病毒(HIV-1和HIV-2)引起的艾滋病,自本世纪80年代发现以来,已传遍全球。据联合国艾滋病总署(UNAIDS)报告,至1997年底,全球感染人数为3060万,1997年新感染580万,死亡230万,累计死亡1170万人.平均每天有1.6万人新感染上HIV,其中90%以上的新感染者是在发展中国家。我国的HIV感染人数正在急剧增长,遍布全国各省市。艾滋病己成为威胁人类的最严重的传染病。因此,许多国家投入巨资(如美国为每年15亿美元以上)从事艾滋病的研究。所以,获得的研究成果也日新月异。近些年来,在艾滋病治疗药物研究和艾滋病发病机理研究等方面取得了突破性进展。由于本文篇幅和作者本人知识所限,本文仅简要介绍HIV与免疫系统相互作用的几个重要方面的新进展。
AIDS caused by the human immunodeficiency virus (HIV-1 and HIV-2) has spread around the world since its discovery in the 1980s. According to the UNAIDS, by the end of 1997, the number of global infections was 30.6 million, with 5.8 million newly infected and 2.3 million dead in 1997. The cumulative death toll was 11.7 million. On average, 16,000 people are newly infected with HIV each day, of which More than 90% of newly infected people are in developing countries. The number of HIV infections in our country is rapidly increasing, covering all provinces and cities in China. AIDS has become the most serious infectious disease that threatens humanity. As a result, many countries have invested heavily (for example, the United States spends more than 1.5 billion U.S. dollars a year) in AIDS research. Therefore, the research results obtained are also changing rapidly. In recent years, breakthroughs have been made in AIDS treatment drug research and AIDS pathogenesis research. Due to the length of this article and the author’s own knowledge, this article only briefly introduces some important aspects of the interaction between HIV and the immune system.