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目的:探讨老年脑梗死患者血清C-反应蛋白(CRP)水平与病情严重程度及预后的关系。方法:测定86例老年脑梗死患者入院时和治疗2周后血清CRP浓度,观察脑梗死灶不同面积CRP含量变化,并对其神经功能缺损进行标准评分,同时与72例健康人血清CRP进行对照。结果:老年脑梗死患者血清CRP浓度明显高于健康对照组(P<0.05);血清CRP浓度随着病灶增加和神经功能缺损程度增加而增加。结论:CRP水平是临床评价脑梗死严重程度和预后的一个重要的生物学指标。
Objective: To investigate the relationship between serum C-reactive protein (CRP) levels and the severity and prognosis of elderly patients with cerebral infarction. Methods: Serum CRP concentrations were measured in 86 elderly patients with cerebral infarction at admission and 2 weeks after treatment. The changes of CRP levels in different areas of cerebral infarction were observed and their neurological deficits were scored. At the same time, serum CRP was compared with 72 healthy people . Results: Serum CRP levels in elderly patients with cerebral infarction were significantly higher than those in healthy controls (P <0.05). Serum CRP levels increased with the increase of lesions and the increase of neurological deficits. Conclusion: The level of CRP is an important biological indicator for clinical evaluation of the severity and prognosis of cerebral infarction.