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目的探讨具有峻泻作用的中药巴豆对家兔奥狄氏括约肌电活动的影响。方法将空腹家兔分为两组,每组8只,一级服生理盐水,另一组服用巴豆煎出液。动物用巴豆后再用阿托品。同时引导并记录所有实验动物奥狄氏括约肌的电变化。结果消化道给予巴豆可以增加奥狄氏括约肌峰电活动的频率。减小峰电位的电压,并且改变峰电的节律。严重巴豆中毒时,其电活动几乎消失。结论阿托品可以对抗巴豆对奥狄氏括约肌的电活动。
Objective To investigate the effect of Croton, a Chinese herb with strong diarrhea on the electrical activity of Oddi’s sphincter in rabbits. Methods Fasting rabbits were divided into two groups, 8 in each group. The first group took normal saline and the other group took croton decoction. Animals use atropine after using Croton. At the same time, the electrical changes of the Oddi’s sphincter in all experimental animals were guided and recorded. The results of gastrointestinal tract administration of croton can increase the frequency of Oddi’s sphincter peak electrical activity. Reduce the peak potential voltage and change the peak power rhythm. Severe croton poisoning, its electrical activity almost disappeared. Conclusion Atropine can counteract the electrical activity of Croton on Oddi’s sphincter.