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ｔ(ｑ :2 2 ) (ｑ :34:ｑ11 2 )转位是ＢＣＲ/ＡＢＬ基因融合的主要原因 ,由此造成费城 (Ｐｈ)染色体 ,它是慢性髓性白血病 (ＣＭＬ)主要标志 ,同时也可存在于急性髓性白血病 (ＡＭＬ)及急性成淋巴白血病 (ＡＬＬ)。ＢＣＲ/ＡＢＬ1重排是个重要的肿瘤分类标志。常规细胞遗传学
The translocation is a major cause of BCR / ABL gene fusion, resulting in the Philadelphia chromosome, which is the major hallmark of chronic myeloid leukemia (CML) May exist in acute myeloid leukemia (AML) and acute lymphoblastic leukemia (ALL). BCR / ABL1 rearrangement is an important tumor classification marker. Conventional cytogenetics