尚未认识的海地妇女围生期心肌病

来源 :世界核心医学期刊文摘(妇产科学分册) | 被引量 : 0次 | 上传用户:likezzz21cn
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Haitian women have a high relative incidence of clinical presentation with peripartum cardiomyopathy (PPCM): an incidence estimated at one case per three hundred live births, a ten-fold occurrence compared to American women. Our Abstract has been to test the hypothesis that some Haitian women may have a forme fruste of PPCM while still without clinical symptoms. Method: A preliminary case-control study was conducted at the Hospital Albert Schweitzer (HAS), Deschapelles, Haiti, in which 25 apparently healthy postpartum women, without cardiovascular symptoms and with a normal cardiovascular clinical examination, were selected from a consecutive list of obstetrical deliveries and screened by echocardiography for left ventricular dysfunction. Result: Four out of 25 patients (16% ) had asymptomatic left ventricular dysfunction that subsequently evolved towards either improvement or deterioration. Supporting evidence for the existence of asymptomatic left ventricular dysfunction or forme fruste PPCM is presented. A hypothetical schema of the pathophysiology of PPCM explains how a latent phase of variable duration may exist prior to onset of detectable clinical heart failure. Conclusion: Screening Haitian women during the last month of pregnancy or in the early postpartum period may help to detect asymptomatic left ventricular dysfunction. Early detection and treatment of PPCM in a known high risk population could lead to improvements in maternal and fetal mortality and morbidity. Haitian women have a high incidence of clinical presentation with peripartum cardiomyopathy (PPCM): an incidence estimated at one case per three hundred live births, a ten-fold occurrence compared to American women. Our Abstract has been to to the hypothesis that some Haitian Method: A preliminary case-control study was conducted at the Hospital Albert Schweitzer (HAS), Deschapelles, Haiti, in which 25 apparently healthy postpartum women, without cardiovascular symptoms and with a normal cardiovascular clinical examination, were selected from a consecutive list of obstetrical deliveries and screened by echocardiography for left ventricular dysfunction. Result: Four out of 25 patients (16%) had asymptomatic left ventricular dysfunction that subsequently evolved to either improvement or deterioration. evidence for the existence of asymptomatic left ventricular dysfunction or forme fru ste PPCM is presented. A hypothetical schema of the pathophysiology of PPCM explain how a latent phase of variable duration may exist prior to onset of detectable clinical heart failure. Conclusion: Screening Haitian women during the last month of pregnancy or in the early postpartum period may help to detect asymptomatic left ventricular dysfunction. Early detection and treatment of PPCM in a known high risk population could lead to improvements in maternal and fetal mortality and morbidity.
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