近年来,由于LHRH脉冲疗法有很好的诱发排卵效果,所以临床上开始应用该方法治疗无月经患者。但也有报道接受LHRH脉冲疗法的无月经妇女约有20％对此疗法无反应,原因至今不明,作者发现LHRH脉冲疗法无效的6例患者中5例属于垂体脱敏现象,并主要从内分泌学角度探讨了脉冲疗法成功例和无效例的差异。 In recent years, due to LHRH pulse therapy has a good ovulation induction effect, so the clinical application of this method began to treat patients without menses. However, it has also been reported that about 20% of women without menstruation receiving LHRH pulse therapy have no response to this therapy. The reason for this is unknown. The authors found that 5 of the 6 patients who failed LHRH pulse therapy belonged to hypothyroidism and were mainly endocrinologically The difference between successful and ineffective cases of pulse therapy was discussed.