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弥漫性系膜增生性肾小球肾炎(DPGN),尤其IgA肾炎在新加坡肾小球肾炎中最为常见的。作者于1979～1981年期间,应用环磷酰胺,潘生丁及小剂量华法令三联对一组DPGN患者进行疗效观察。材料和方法 52对DPGN患者入院时均经肾活检,随机分为治疗组和对照组。治疗组给予环磷酰胺1.5mg/kg/d共6个月,潘生丁300mg/d共36个月,华法令1.5—3mg/d并给予降压和利尿药物控制高血压和水肿。对照组给予降压和利尿药。观察
Diffuse mesangial proliferative glomerulonephritis (DPGN), especially IgA nephritis, is most common in glomerulonephritis in Singapore. The author from 1979 to 1981 period, the application of cyclophosphamide, dipyridamole and low-dose warfarin triple in a group of patients with DPGN efficacy. Materials and methods 52 pairs of DPGN patients were admitted to the hospital by renal biopsy, were randomly divided into treatment group and control group. The treatment group was given cyclophosphamide 1.5mg / kg / d for 6 months, dipyridamole 300mg / d for 36 months, warfarin 1.5-3mg / d and given antihypertensive and diuretic drugs to control hypertension and edema. The control group was given antihypertensive and diuretic drugs. Observed