Porous rock chemical grouting simulation test was conducted using established large scale physical model.Chemical grout diffusing rule in porous media with different permeability was studied by monitoring the spontaneous potential and exciting current response during grouting.The results show that chemical grout spread evenly in all directions and diffusion areas are approximately concentric circles in the cross section of homogeneous transverse isotropic pore medium,the grout spread flling range can be quantitatively decrypted by the diffusion radius.The average diffusion speed and radius increase approximately as the square root with the permeability coeffcient in different permeability media under the same conditions.Calculation results using Maag cylindrical diffusion equation show that the calculated value of diffusion radius is in good agreement with the test value under different grouting pressures and permeability conditions. Porous rock chemical grouting simulation test was conducted using established large scale physical model. Chemical grout diffusing rule in porous media with different permeability was studied by monitoring the spontaneous potential and exciting current response during grouting.The results show that chemical grout spread evenly in all directions and diffusion areas are approximately concentric circles in the cross section of homogeneous transverse isotropic pore medium, the grout spread flling range can be quantitatively decrypted by the diffusion radius. the average diffusion speed and radius increase approximate as the square root with the permeability coeffcient in different permeability media under the same conditions. Calculating results using Maag cylindrical diffusion equation show that the calculated value of diffusion radius is in good agreement with the test value under different grouting pressures and permeability conditions.