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痛经和月经量过多是引起取出宫内节育器(IUCD)的主要原因。节育器可引起子宫内膜组织损伤,发生炎症过程;可引起粘膜局部释放过量的前列腺素,使子宫的活动性、紧张性增强,强烈的子宫收缩引起子宫血循环受阻导致局部缺血,从而使原有痛经加重;另外,节育器还引起粘膜局部释放过量的组织胺等,使毛细血管脆性提高,纤维蛋白溶解活动增强,造成月经量增多。作者曾对原发痛经患者用naproxen和安慰剂双盲法进行临床试验,发现naproxen使痛经减轻,月经血量减少。本文报告了用naproxen治疗带
Dysmenorrhea and excessive menstrual flow are the main causes of IUCD removal. IUD can cause damage to endometrial tissue, the occurrence of inflammatory processes; can cause mucosal excessive release of prostaglandins, uterine activity, increased tension, uterine contraction caused by a strong impediment caused by blocked blood circulation leading to ischemia, so that the original Dysmenorrhea worse; In addition, the IUD also caused mucosal release of excess histamine, the capillary fragility increased fibrinolytic activity, resulting in increased menstrual flow. The author of primary dysmenorrhea patients with naproxen and placebo double-blind clinical trials found that naproxen to reduce dysmenorrhea, menstrual blood reduced. This article reports the treatment of naproxen bands