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目的总结儿童手足口病(HFMD)临床表现和诊治体会,探讨其危险因素及对疗效影响。方法对HFMD患儿资料作回顾性总结分析及流行病学分析。结果普通病例组平均住院日与重症病例组比较差异有统计学意义(P<0.01);普通病例组与对照组之间,WBC比较差异无统计学意义(P>0.05)。LYM%和GRAN%的比较差异有统计学意义(P<0.01),重症病例组与普通病例组之间LYM%和GRAN%的比较差异有统计学意义(P<0.01)。急性期与恢复期患者LYM%、GRAN%、Mono%LYM%、GRAN%、Mono%比较差异均有统计学意义(P<0.01)。结论患者就诊时间越及时可以降低发展成为危重病人的风险。在临床应用中可加强对GRAN%这个易于检测的指标的认识,对病情进行病情观察、动态评估和预后判断,并以此作为手足口病患者短期内发展为危重病例的重要参考指标。
Objective To summarize the clinical manifestations, diagnosis and treatment of hand, foot and mouth disease (HFMD) in children and to explore its risk factors and their effects on the curative effect. Methods The data of HFMD patients were retrospectively summarized and analyzed. Results There was significant difference between the average hospitalization days and the severe cases in the common case group (P <0.01). There was no significant difference in the WBC between the common case group and the control group (P> 0.05). There was significant difference between LYM% and GRAN% (P <0.01). There was significant difference in LYM% and GRAN% between severe cases and common cases (P <0.01). There were significant differences in LYM%, GRAN%, Mono% LYM%, GRAN%, Mono% between acute phase and convalescent phase (P <0.01). Conclusions The more timely the patient visit, the lower the risk of developing into a critically ill patient. In clinical application, it is possible to strengthen the understanding of GRAN%, an easily detectable index, to observe the condition, evaluate the prognosis and judge the prognosis of the disease, and use it as an important reference index for the short-term development of HFMD in critically ill patients.