【摘 要】
:
The primarypremature ejaculation (PPE) is a common male sexual disorder.We proposed a novel behavioral therapy for PPE through regular penis-root masturbation (PRM).Nine heterosexual men with PPE completed the self-controlled study.After a 3-month PRM tra
【机 构】
:
Department of Infertility and Sexual Medicine, The Third Affiliated Hospital of Sun Yat-sen Universi
论文部分内容阅读
The primarypremature ejaculation (PPE) is a common male sexual disorder.We proposed a novel behavioral therapy for PPE through regular penis-root masturbation (PRM).Nine heterosexual men with PPE completed the self-controlled study.After a 3-month PRM training,the median intravaginal ejaculatory latency time (IELT) increased from 60 s to 180 s (P =0.018),and the mean Premature Ejaculation Diagnostic Tool (PEDT) score decreased from 14.8 ± 3.7 to 12.8 ± 4.1 (P =0.074).Five out of eight patients had the prolonged dorsal nerve somatosensory evoked potential (DNSEP).The results suggest that PRM has a short-term therapeutic effect.Randomized controlled trials are needed to validate the efficacy.
其他文献
In the present study, we evaluated the impact of sperm origins and concentration on the clinical outcomes of intracytoplasmic sperm injection (ICSI) cycles. A total of 1201 ICSI cycles were retrospectively analyzed for male azoospermia or oligozoospermia
The epithelium of the human epididymis maintains an appropriate luminal environment for sperm maturation that is essential for male fertility.Regional expression of small noncoding RNAs such as microRNAs contributes to segment-specific gene expression and
Calpain activation contributes to hyperglycemia-induced endothelial dysfunction and apoptosis.This study was designed to investigate the role of calpain inhibition in improving diabetic erectile dysfunction (ED) in mice.Thirty-eight-week-old male C57BL/6J
Although elevated prolactin levels have been shown to inhibit penile erection,the relationship between prolactin and erection of the penile tip or base has not been extensively researched.We therefore investigated the prolactin\'s effects on erection of
Androgen receptor (AR),a hormonal transcription factor,plays important roles during prostate cancer progression and is a key target for therapeutic interventions.While androgen-deprivation therapies are initially successful in regressing prostate tumors,t
The stromal antigen 3 (STAG3) gene,encoding a meiosis-specific cohesin component,is a strong candidate for causing male infertility,but little is known about this gene so far.We identified STAG3 in patients with nonobstructive azoospermia (NOA) and normoz
Prostate cancer is characterized by bone metastases and difficulty of objectively measuring disease burden.In this context,cell-free circulating tumor DNA (ctDNA) and circulating tumor cell (CTC) quantitation and genomic profiling afford the ability to no
Despite impressive survival benefits with immunotherapy in patients with various solid tumors,the full potential of these agents in prostate cancer has yet to be realized.Sipuleucel-T demonstrated a survival benefit in this population,indicating that pros
As men grow older, circulating testosterone declines while the incidence of cardiovascular disease increases. Thus, the role of sex hormones as biomarkers, and possibly contributing factors to clinical manifestations of cardiovascular disease in the incre
Dear Editor,rnVaricocele is a common cause of male infertility,but in the course of a diagnostic infertility workup,other underlying problems are often found.Up to two-thirds of patients with nonidiopathic male infertility have at least two possible etiol