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目的：探讨积极性社区干预对慢性精神分裂症的综合疗效。方法：将104例社区慢性精神分裂症患者随机分为干预组和对照组，各52例，干预组予积极性社区干预治疗，对照组接受传统社区精神卫生服务，随访观察1年。分别在实施干预前、干预6月末、干预1年末采用阳性与阴性症状量表（Positive and Negative Syndrome Scale， PANSS）、威斯康星量表（Wisconsin Card Sorting Test，WCST）、精神分裂症患者生活质量量表（Quality of Life Scale， SQLS）、社会功能缺陷筛选量表（Social Disability Screening Schedule，SDSS）评估患者临床症状、认知功能、生存质量以及社会功能。结果：治疗1年末，干预组复发率、住院率分别为9．62％、1．92％，对照组分别为15．38％、5．77％，两组间差异均无统计学意义（χ2＝0．791，P＝0．374；χ2＝0．260，P＝0．610）。治疗后两组患者临床症状均有明显改善，与治疗前比较，干预组干预6月、1年末 PANSS总分和各因子分、WCST、SQLS和SDSS评分均明显改善；对照组干预1年末PANSS总分和一般精神病理评分较治疗前明显改善，WCST、SQLS和SDSS评分较治疗前均无明显改变。干预组治疗1年末PANSS 总分、阴性症状评分、WCST、SQLS 和 SDSS 评分改善程度均优于对照组（P＜0．05）。结论：积极性社区干预在改善精神分裂症患者临床症状的同时，能促进认知功能恢复，提高生存质量和社会功能。“,”Objective:To explore the effect of active community intervention(ACI)on patients with chronic schizophrenia.Methods:One hundred and four patients with chronic schizophrenia were ran-domly divided into intervention group(n=52)and control group(n=52);patients in intervention group were treated with ACI,while patients in control group were received traditional community mental health services,all the patients were followed up for 1 year.Positive and Negative Syndrome Scale (PANSS), Wisconsin Card Sorting Test (WCST),Quality of Life Scales (SQLS )and Social Disability Screening Schedule(SDSS)were used to assess the clinical symptoms,cognitive function,quality of life and social function before and 6 months,1 year after the follow-up.Results:One year after intervention,there were no statistical differences in the relapse and hospitalization rate between the two groups(χ2 =0.791, P=0.374;χ2 =0.260,P=0.610).The clinical symptoms of the two groups patients were all improved significantly.As compared with the condition before treatment,the intervention group at the end of 6 month,1 year after treatment,the total score and each factor score of PANSS,the WCST,SQLS and SDSS score were all improved significantly.The control group at 1 year after treatment,the total score and general mental pathological score of PANSS were improved significantly,while the WCST,SQLS andSDSS score had no obvious change.Comparison between the two groups,the total score of PANSS and Negative score in the intervention group were significantly lower than those in control group 1 year after treatment(P<0.05).At the same time,the total score of WCST,SQLS and SDSS in intervention group were all significantly better than those in control group after 1 year treatment.Conclusion:ACI could im-prove the clinical symptoms and promote the cognitive function in patients with chronic schizophrenia,at the same time could improve the quality of life and social functions.