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目的了解待产孕妇中细菌性阴道病(BV)支原体的检出率以及药敏的情况。方法回顾性分析2016年1月-12月在本院确诊BV的待产孕妇合并支原体感染的情况及药敏结果。结果本院2016年1月-12月的待产孕妇2 254例细菌性阴道病患者中感染支原体1 285例,总检出率为57.0%。其中感染人型支原体28例,检出率为1.2%。感染解脲支原体1 005例,检出率为44.6%。同时感染人型支原体和解脲支原体的252例,检出率为11.2%。支原体对美满霉素、强力霉素和交沙霉素较为敏感,耐药率均≤6.5%,对氧氟沙星、左旋氧氟沙星、司帕沙星类喹诺酮类药物耐药率高,耐药率均>72%。结论细菌性阴道病待产孕妇中检出支原体感染率较高,临床应根据药敏结果合理选择药物治疗。
Objective To understand the detection rate of mycoplasma and bacterial susceptibility to bacterial vaginosis (BV) in expectant mothers. Methods Retrospective analysis of the cases of mycoplasma infection in pregnant women with confirmed BV who were diagnosed in our hospital from January to December in 2016 and their drug susceptibility results were retrospectively analyzed. Results A total of 1,285 cases of mycoplasma were found in 2 254 cases of bacterial vaginosis from January 2016 to December 2016 in our hospital. The total detection rate was 57.0%. Among them, 28 cases were infected with Mycoplasma hominis, the detection rate was 1.2%. 1 005 cases of Ureaplasma urealyticum infection, the detection rate was 44.6%. 252 cases infected with Mycoplasma hominis and Ureaplasma urealyticum at the same time, the detection rate was 11.2%. Mycoplasma was more sensitive to minocycline, doxycycline and josamycin, the resistance rates were all less than or equal to 6.5%, high resistance to ofloxacin, levofloxacin, sparfloxacin quinolones, Resistance rates were> 72%. Conclusions The prevalence of mycoplasma infection in patients with bacterial vaginosis to be pregnant is high, and the clinical treatment should be based on the drug susceptibility results.