分枝杆菌是广泛存在于自然界中的微生物，包括致病菌和机会致病菌。分枝杆菌的感染谱是非常广的，它可以使多种动物和人类致病，如结核分枝杆菌可以引起人类的结核病等。人类的克隆氏病[1]（Crohn氏病或CD）是Crohn于1932年首次发现的。之后，世界各国学者对克隆氏病的致病因素 Mycobacteria are microorganisms that are widespread in nature, including pathogenic bacteria and opportunistic pathogens. Mycobacterium infection spectrum is very broad, it can make a variety of animal and human pathogenic, such as Mycobacterium tuberculosis can cause human tuberculosis and so on. Human Crohn’s disease [1] (Crohn’s disease or CD) was first discovered by Crohn in 1932. Since then, scholars from all over the world have made the etiological factor for Crohn’s disease