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通过研究发现,在进展期胃癌中表皮生长因子受体2存在基因扩增或过表达。Her-2阳性的胃癌与其组织学类型及原发部位密切相关,并且当前对于Her-2阳性是否对患者预后有指导意义仍在研究阶段。本文主要介绍了Her-2在胃癌中的表达、Her-2与胃癌预后的相关性及抗Her-2靶向药物在Her-2阳性胃癌治疗中的现状进行了介绍。
Through the study found that epidermal growth factor receptor 2 in advanced gastric cancer gene amplification or overexpression. Her-2-positive gastric cancer is closely related to its histological type and primary site, and it is still at the research stage whether Her-2 positivity is a guideline for the prognosis of patients. This article mainly introduces the expression of Her-2 in gastric cancer, the relationship between Her-2 and the prognosis of gastric cancer and the current situation of anti-Her-2 targeted therapy in the treatment of Her-2 positive gastric cancer.