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锂盐是治疗某些精神疾患的药物,关于锂的吸收和排泄以及血药浓度等数据已有报导,并已收载入某些教科书。但是锂在体内的分布尚未见报导,作者分别测定了对照组和给药组家兔脑、肾、肝、心、胆、肌肉、血清、血浆、红细胞等组织中的锂含量,简报如下: 一、实验设计健康家兔10只,体重约2kg。给药组8只,空白对照组2只,雌雄各半。药品:药用碳酸锂(纯度99％)。给药组参照成人患者剂量20mg/kg/天给药(碳酸锂配成2mg/ml水溶液,
Lithium salts are drugs for the treatment of certain mental disorders. Data on lithium absorption and excretion and plasma concentrations have been reported and have been included in some textbooks. However, the distribution of lithium in the body has not been reported yet. The authors determined the lithium content in the brain, kidney, liver, heart, gall bladder, muscle, serum, plasma and erythrocytes of the control group and the administration group, respectively, Experimental design of healthy rabbits 10, weighing about 2kg. There were 8 rats in the administration group and 2 in the blank control group, which were male and female. Drugs: Medicinal lithium carbonate (purity 99%). Administration group reference adult patients dose 20mg / kg / day administration (lithium carbonate dubbed 2mg / ml aqueous solution,