目的 探讨125例Graves病 (GD)患者组、51例GD治疗恢复组及72例正常健康者 (HG)血清催乳素 (PRL)水平。方法 用RIA法测清晨空腹血清PRL,GD组同时送测TT3、TT4、rT3、FT4、TGA、TMA ,用IRMA法测TSH。结果 GD组血清PRL水平较CG组明显升高(P<0.01) ,且随病情恢复而降低 (P<0.05)。 结论 提示血清PRL参与Graves病患者的免疫病理机制 Objective To investigate the serum levels of prolactin (PRL) in 125 patients with Graves disease (GD), 51 patients with GD and 72 healthy controls (HG). Methods Fasting serum (PRL) was measured by RIA method, and TT3, TT4, rT3, FT4, TGA and TMA were measured at the same time. The TSH was measured by IRMA. Results The level of serum PRL in GD group was significantly higher than that in CG group (P <0.01), and decreased with the recovery of disease (P <0.05). Conclusion Conclusions Serum PRL is involved in the immunopathogenesis of Graves disease