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目的:观察中药联合激光穴位照射治疗小儿复发性过敏性紫癜的临床疗效。方法:将116例反复发作性过敏性紫癜患儿随机分为治疗组与对照组,每组各58例,治疗组予中药联合激光穴位照射治疗,对照组予西药左西替利嗪片和双嘧达莫治疗,两组疗程1个月,并随访1年。并检测该116例患者的血清过敏原特异性IgE,比较治疗组及对照组患儿经治疗后血清过敏原特异性IgE测定结果。结果:治疗组在临床症状消退时间、疗效及复发率上均明显优于对照组。两组患儿在治疗后,治疗组血清过敏原特异性IgE阳性人数及比例比对照组低,P均<0.05,具有统计学意义。结论:口服中药联合激光穴位照射治疗小儿复发性过敏性紫癜疗效显著,且无明显不良反应,值得临床推广应用。
Objective: To observe the clinical efficacy of Chinese medicine combined with laser acupoint irradiation in the treatment of children with recurrent anaphylactoid purpura. Methods: One hundred and sixty-six children with recurrent Henoch-Schonlein purpura were randomly divided into treatment group and control group, with 58 cases in each group. The treatment group was treated with traditional Chinese medicine combined with laser acupuncture and the control group was given Western medicine levocetirizine tablets and bis Pyrapyramide treatment, two courses of treatment for 1 month, followed up for 1 year. Serum allergen-specific IgE was detected in 116 patients, and serum allergen-specific IgE was compared between the treatment group and the control group. Results: The treatment group was significantly better than the control group in clinical symptoms subsided time, efficacy and recurrence rate. After treatment, the number and proportion of serum allergen-specific IgE positive patients in the two groups were lower than those in the control group (all P <0.05), which was statistically significant. Conclusion: Oral Chinese medicine combined with laser acupoint irradiation treatment of children with recurrent anaphylactoid purpura significant effect, and no significant adverse reactions, it is worth promoting the clinical application.