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目的:对儿童过敏性紫癜的诱因、病因、相应的临床表现以及预后进行研究探讨,以提高对该病的认识、诊断和治疗水平。方法:选取2010年3月至2012年3月我院收治的68例儿童过敏性紫癜患者的临床病例进行回顾性分析,对儿童过敏性紫癜患者的病因、病史、临床特征、实验室检查以及治疗方案进行总结分析。结果:多发年龄主要为3～13岁,平均(8.31±3.87)岁;冬春季节发病率较高,可占全年的84.1%;主要的发病诱因是感染;患者的主要临床症状为典型的皮肤紫癜,若出现首发症状为消化道症状的病例时,需要严加诊断,避免误诊;有35.4%的病例出现肾受损症状,伴有肾损害的患者病程会延长,甚至迁延数年。结论:过敏性紫癜在学龄期儿童中较为多见,多发于冬春季节,发病的主要诱因是感染,所以需要及早诊断并进行治疗,早期规范的综合治疗的临床疗效显著,具有临床推广价值。
Objective: To investigate the causes, etiologies, clinical manifestations and prognosis of Henoch-Schonlein purpura in children so as to improve their understanding, diagnosis and treatment of this disease. Methods: The clinical data of 68 children with Henoch-Schonlein Purpura who were admitted to our hospital from March 2010 to March 2012 were retrospectively analyzed. The etiology, history, clinical features, laboratory tests and treatment of children with Henoch-Schonlein purpura Program summary analysis. Results: The multiple age was mainly from 3 to 13 years old, with an average of (8.31 ± 3.87) years old. The incidence in winter and spring was high, accounting for 84.1% of the whole year. The main cause of infection was infection. The main clinical symptoms were typical Skin purpura, if the first symptoms of gastrointestinal symptoms appear cases, the need for strict diagnosis, to avoid misdiagnosis; 35.4% of cases of renal damage symptoms, with renal damage in patients with the duration will be extended, or even delayed for several years. Conclusion: Allopathic purpura is more common in school-age children and occurs mainly in winter and spring. The main cause of this disease is infection. Therefore, it is necessary to diagnose and treat early. The clinical curative effect of early normative comprehensive treatment is significant and has clinical value of popularization.