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本文对静脉血栓患者预测肝素输注速率的两种方法进行了比较。一种方法是根据单室药物动力学模型,另一种方法是根据病人的体重。将68例受试者分成二组,组1病人的初注速率是根据病人的体重(77单位/kg/4小时)确定,组2的初注速率是根据单室肝素模型的动力学方程式来确定:
This article compares two methods of predicting heparin infusion rates in patients with venous thromboembolism. One method is based on a single-compartment pharmacokinetic model and the other method is based on the patient’s body weight. Sixty-eight subjects were divided into two groups. The initial bolus rate for group 1 patients was based on the patient’s body weight (77 units / kg / 4 hours) and the initial bolus rate for group 2 was based on the kinetic equation for the univalve heparin model determine: