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病例和方法 7例慢性或间歇性特发性血小板减少性紫癜(ITP)中,3例作过脾切除,这3例中有2例(例1、2)虽经免疫抑制治疗仍有出血发作(经过至少1年,当治疗中断时,血小板数立即降至<3万/mm~3),例3间歇用强的松维持血小板在3万～10万/mm~3。未作脾切除的4例中有1例(例4)对强的松有抗药性(在最后6个月中血小板数为0.5万～9.7万/mm~3)。2例为强的松依赖者(例5、6,血小板数至少在18个月中为4万～12万/mm~3)。例7完全缓解,但数年后复发。6例急性ITP儿童中,2例对强的松
Case and Method Three of 7 patients with chronic or intermittent idiopathic thrombocytopenic purpura (ITP) underwent splenectomy. Of the 3 patients, 2 patients (Examples 1 and 2) had bleeding episodes despite immunosuppressive therapy (After at least 1 year, when the treatment is interrupted, the number of platelets immediately drops to <30,000 / mm ~ 3). Example 3 Intermittent prednisolone platelets in 30,000 ~ 100,000 / mm ~ 3. One of the four cases without splenectomy (Example 4) was resistant to prednisone (platelets ranged from 50 000 to 97 000 / mm 3 in the last 6 months). 2 were prednisone-dependent (cases 5 and 6, with platelets at 40,000 to 120,000 / mm 3 for at least 18 months). Case 7 complete remission, but relapse after a few years. Of the 6 acute ITP children, 2 were prednisone