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酰化刺激蛋白途径缺陷是引起脂肪细胞捕获脂肪酸功能障碍的一个主要原因，继而引起甘油三酯代谢异常，并与冠心病之间存在密切关系。酰化刺激蛋白途径缺陷可能具有致动脉粥样硬化的作用
Acylation-stimulating protein pathway defects are one of the major causes of fatty acid trapping in fat cells, which in turn triggers the abnormal metabolism of triglycerides and is closely related to coronary heart disease. Acylation-stimulatory protein pathway defects may have atherogenic effects