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目的探讨缩宫素联合钙剂和米索前列醇在预防及治疗产后出血的临床疗效。方法采用前瞻性对照研究,选择初产妇400名,实验组:取剖宫产产妇100名,自然分娩产妇100名,分娩期间用(缩宫素、10%葡萄糖酸钙、米索前列醇),对照组:取剖宫产产妇100名,自然分娩产妇100名,分娩期间用(缩宫素),分别比较两组产时、产后2小时及产后24小时的累积出血量。结果实验组中行剖宫产的产妇术中、术后2小时、术后24小时累积出血量,均明显低于对照组的剖宫产产妇,差异有统计学意义(P<0.05)。实验组中经阴道分娩的产妇第三产程、产后2小时、产后24小时累积出血量均明显低于对照组的经阴道分娩产妇,差异有统计学意义(P<0.05)。结论缩宫素联合钙剂和米索前列醇预防及治疗产后出血疗效明显,值得在自然分娩及剖宫产时应用推广。
Objective To investigate the clinical efficacy of oxytocin combined with calcium and misoprostol in the prevention and treatment of postpartum hemorrhage. Methods A prospective controlled study was conducted in which 400 primiparae were selected. In the experimental group, 100 cesarean section women and 100 women were delivered spontaneously. During labor, oxytocin, 10% calcium gluconate and misoprostol were used. Control group: taking 100 cesarean section maternal, natural delivery of maternal 100, during childbirth (oxytocin), respectively, when the two sets of birth, 2 hours postpartum and 24 hours after delivery, the cumulative amount of bleeding. Results The cesarean section maternal operation in the experimental group, 2 hours after surgery, 24 hours after the cumulative blood loss, were significantly lower than the control group of cesarean section maternal, the difference was statistically significant (P <0.05). The vaginal delivery in the experimental group of third trimester of labor, 2 hours postpartum, 24 hours postpartum cumulative hemorrhage were significantly lower than the control group of vaginal delivery mothers, the difference was statistically significant (P <0.05). Conclusion oxytocin combined with calcium and misoprostol prevention and treatment of postpartum hemorrhage significant effect, it is worth in the natural childbirth and cesarean section to promote the application.