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目的:研究血液中丙型肝炎病毒核糖核酸(HCV RNA)载量与肝功能及白蛋白(ALB)等指标间的相关性,探讨病毒含量和肝组织损伤之间的关系.方法:选取193例大连地区汉族人群HCV感染患者为研究对象,检测血液中HCV RNA病毒载量,同时测定谷丙转氨酶(ALT)、谷草转氨酶(AST)、AST/ALT及ALB等指标.用豆形图展示HCVRNA病毒载量数据,分析HCVRNA载量与各指标间的相关性.结果:不同性别组HCV RNA载量分布差异无统计学意义(P＞0.05);HCV RNA载量与年龄不存在显著的相关性(P＞0.05). HCV RNA载量与ALT、AST、AST/ALT及ALB均不相关(P＞0.05).根据受试者HCV RNA载量数量级将其分为4组,ALT、AST、AST/ALT及ALB在各组间差异无统计学意义(P＞0.05).结论:大连地区汉族人群HCV患者血液中HCV RNA载量与ALT、AST、AST/ALT及ALB等指标不相关,HCV RNA病毒载量不能反映肝脏损伤程度.“,”Objective:To investigate the relationship between HCV RNA load and liver function and ALB in HCV infected patients. Method:The HCV RNA viral load and ALT,AST, AST/ALT and ALB were measured in 193 Dalian Han HCV infected patients. The HCV RNA viral load data were presented by beanplots,and the correlations between HCV RNA load and each index were analyzed. Result:Gender and age could not affect HCV RNA viral load in HCV infected patients. HCV RNA viral load was not correlated with ALT, AST, AST/ALT and ALB. In addition, we divided the patients into four groups according to HCV RNA viral load,and ALT, AST, AST/ALT and ALB were not significantly different among the groups. Conclusion:Our results showed that HCV RNA load in Dalian Han HCV infected patients was not related to ALT, AST, AST/ALT and ALB, that is,the HCV RNA load could not reflect the degree of liver injury.