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儿童单纯肥胖的发生率呈快速增长趋势,经研究证实其原因是由遗传因素、不良生活方式等环境因素共同作用的结果。寻找与环境因素相互作用的基因受到特别关注。现已查明瘦素就属于这种基因。为此,应对瘦素的生理功能,瘦素与儿童单纯肥胖症相关的孕母血浆瘦素水平、瘦素与脂肪代谢和心血管疾患的关系、性别对体内的瘦素变化的影响、瘦素基因变异等问题加以探讨,为控制儿童肥胖症采取科学措施提供依据。
The incidence of childhood simple obesity showed a rapid growth trend, the study confirmed that the reason is due to genetic factors, unhealthy lifestyles and other environmental factors together. The search for genes that interact with environmental factors is of particular concern. It has been identified that leptin belongs to this gene. To this end, to deal with the physiological function of leptin, leptin and simple obesity in children related to maternal plasma leptin levels, the relationship between leptin and fat metabolism and cardiovascular disease, gender changes in the body of leptin, leptin Gene mutation and other issues to be explored to provide scientific basis for the control of childhood obesity.