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将成年小白鼠通过人为的骨折与烧伤造成“外伤及肾”的动物模型。实验结果发现模型组小白鼠睾丸有退行性变化,精子成熟过程受阻;电镜下又见脑垂体促性腺激素细胞胞浆内颗粒减少、核固缩及空泡变性和出血等现象,说明急病及肾在病理形态上的改变主要表现在垂体—性腺轴上,这在肾本质实验研究方面是一个新的进展。
The adult mouse is caused by an artificial fracture and burn to create an animal model of “trauma and kidney.” The experimental results showed that mice in the model group had degenerative changes in the testes, and the sperm maturation process was blocked; electron microscopy also showed cytoplasmic granule loss, nuclear pyknosis, vacuolar degeneration, and hemorrhage of pituitary gonadotropin cells, indicating that acute disease and kidneys The pathological changes mainly in the pituitary - gonadal axis, which is a new progress in the experimental study of renal nature.