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钾通道开放剂如ｃｒｏｍａｋａｌｉｍ和 ｐｉｎａｃｉｄｉｌ,具有激活心肌和平滑肌等组织ＡＴＰ敏感性钾通道 (ＫＡＴＰ)的作用[1,2 ] ,临床已用于治疗高血压和保护缺血心肌。在离体血管实验中发现 ,ｃｒｏｍａｋａｌｉｍ扩血管作用具有温度依赖性[3 ] 。本研究旨在观察不同实
Potassium channel openers such as cromakalim and pinacidil have the potential to activate ATP-sensitive potassium channels (KATP) in tissues such as myocardium and smooth muscle [1,2]. They have been used clinically to treat hypertension and protect ischemic myocardium. In ex vivo vascular experiments, cromakalim vasodilator was found to be temperature-dependent [3]. This study aims to observe different facts