硫糖铝已用于治疗胃十二指肠溃疡、回流性食管炎和糜烂性胃肠道出血。Carling等已用该药治疗结肠炎。作者报告硫糖铝灌肠治疗22例不同病因的直肠溃疡病变。 22例患者,其中8例为照射性直肠炎,5例自发性溃疡性直肠炎,5例孤立性直肠溃疡,4例直肠息肉。除4例息肉患者外所有患者都用过常规药物治疗至少4周无效。4例直肠息肉都有溃疡和充血。10%硫糖铝水悬液(硫糖铝2 g,加水20 ml)注入直肠内,每 Sucralfate has been used to treat gastroduodenal ulcers, reflux esophagitis, and erosive gastrointestinal bleeding. Carling and others have used the drug to treat colitis. The authors report sucralfate enema treatment of 22 cases of different causes of rectal ulcer lesions. Twenty-two patients, including 8 cases of irradiation proctitis, 5 cases of spontaneous ulcerative proctitis, 5 cases of solitary rectal ulcer, 4 cases of rectal polyps. All patients except 4 polyp patients were treated with conventional medication for at least 4 weeks. 4 cases of rectal polyps have ulcers and congestion. 10% sucralfate suspension (sucralfate 2 g, add water 20 ml) into the rectum, each