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近年来,H_2受体拮抗剂在消化性溃疡的治疗中起着十分重要的作用,临床医师日益重视治疗药物的选择。努力探求新药以控制胃酸分泌、保护粘膜屏障机制的完整性正方兴未艾。目前突出的问题是药物停用或长期维持治疗后如何防止溃疡病的复发。组胺H_2受体拮抗剂近来,在采用西咪替丁(甲氰咪胍)和雷尼替丁的治疗中,侧重于给药方式上的改变。一般认为,完全抑制胃酸分泌并不理想,降低
In recent years, H 2 receptor antagonists play a very important role in the treatment of peptic ulcer. Clinicians pay more and more attention to the selection of therapeutic drugs. Efforts to explore new drugs to control gastric acid secretion, protect the integrity of the mucosal barrier mechanism is in the ascendant. The most prominent issue at the moment is how to prevent the recurrence of ulcer disease after drug discontinuation or long-term maintenance treatment. Histamine H 2 Receptor Antagonists Recently, in the treatment with cimetidine (cimetidine) and ranitidine, emphasis has been placed on the mode of administration. Generally believed that the complete inhibition of gastric acid secretion is not ideal, lower