从1984年以来,瑞典曾多次发生小规模白喉爆发,大多数病人及所有病死者都是成人。对成人复种的间隔时间或疫苗剂量尚无一致意见,本文对改进剂量的白喉、破伤风类毒素(DT)加强注射效果进行了评价。作者对36名平均年龄为30岁(23～43岁)的健康成人志愿者(男28人,女8人),接种DT(含白喉类毒素25Lf/mL,破伤风类毒素 Since 1984, small-scale outbreaks of diphtheria have taken place in Sweden many times, with most patients and all those killed being adults. There is no consensus on interval or vaccination doses for multiple seeding in adults. In this paper, we evaluated the enhanced doses of diphtheria and tetanus toxoid (DT) injections. Thirty-six healthy adult volunteers (28 males and 8 females) with a mean age of 30 years (23-43 years), DT (diphtheria toxoid 25 Lf / mL, tetanus toxoid