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已知糖尿病患者可表现为血清T_4正常、T_3降低的所谓低T_3综合征,但对其原因和意义的了解尚不充分。本研究调查了糖尿病患者的甲状腺功能,以观察其发生低T_3综合征的百分率,和易与何种糖尿病并存。 50例连续入院的糖尿病患者,均无临床甲状腺功能异常,并除外甲状腺肿大者。男女各25例,年龄12～78(平均54.7)岁。在研究时均未接受治疗,且无酮症酸中毒。对全部患者进行血清T_(?)、T_3、rT_3、FT_4、TBG和TSH及甲状腺自身抗体测定。有持继性蛋白尿者为糖尿病肾病,眼底表现符合Scott分类Ⅰ级以上者为视网膜病变。
Diabetes is known to be characterized by a so-called low T 3 syndrome with normal T_4 serum and reduced T_3 but insufficient knowledge of its causes and implications. This study investigated thyroid function in patients with diabetes mellitus to see if they had a low T 3 syndrome and what type of diabetes mellitus coexisted with. 50 cases of consecutive hospitalized patients with diabetes, no clinical thyroid dysfunction, with the exception of goiter. 25 men and women each, aged 12 to 78 (average 54.7) years old. In the study were not treated, and no ketoacidosis. Serum T_ (?), T_3, rT_3, FT_4, TBG and TSH and thyroid autoantibodies were measured in all patients. Those with progressive proteinuria were diabetic nephropathy, retinal manifestations consistent with Scott classification Ⅰ grade for retinopathy.