慢性重型肝炎是在慢性肝炎或肝硬化基础上出现的亚急性肝坏死 ,其病情虽不如急性或亚急性重型肝炎那样进展迅速 ,但在乙型肝炎发病率较高的我国 ,临床上更为常见。一旦出现并发症 ,临床预后差 ,病死率高 ,因而早期治疗、及时阻断肝细胞的进一步坏死就尤为重要。前列腺素Ｅ １( Chronic severe hepatitis is subacute hepatic necrosis on the basis of chronic hepatitis or cirrhosis, its condition is not as rapid as acute or subacute severe hepatitis, but in our country with a higher incidence of hepatitis B, it is more common clinical . In the event of complications, the clinical prognosis is poor, high mortality, which early treatment, timely blocking of further necrosis of liver cells is particularly important. Prostaglandin E 1 (