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[目的]探讨平移扫描式全身放疗在恶性肿瘤骨转移中的疗效和安全性。[方法]回顾性分析2006年4月至12月接受全身治疗5例多处骨转移恶性肿瘤患者的临床资料。[结果]4例患者按预定计划完成放疗,1例患者因Ⅳ度骨髓抑制中断治疗13d。5例患者全身放疗后疼痛完全缓解。1例骨转移病灶完全消失,4例溶骨性病灶部分缩小、钙化。随访至2009年6月,2例存活,3例死亡。治疗期间1例出现Ⅰ度骨髓抑制,4例出现Ⅲ～Ⅳ度骨髓抑制,无视力障碍、放射性肺炎和肝肾、心脏损伤。[结论]平移扫描式全身放疗对多处骨转移患者是一项有效的姑息治疗手段,毒性反应可耐受。
[Objective] To investigate the efficacy and safety of pan-scan generalized radiotherapy for bone metastases of malignant tumors. [Methods] The clinical data of 5 patients with multiple malignant tumor of bone metastasis receiving systemic treatment from April to December 2006 were retrospectively analyzed. [Results] Four patients completed radiotherapy according to the scheduled schedule and one patient was interrupted by Ⅳ degree myelosuppression for 13 days. Five patients had complete remission of pain after radiotherapy. One case of bone metastases completely disappeared, 4 cases of osteolytic lesions partially reduced, calcification. Followed up to June 2009, 2 survived and 3 died. One case had myelosuppression in one case, three to four degrees myelosuppression in four cases, no visual impairment, radiation pneumonitis and liver, kidney and heart damage. [Conclusion] Translational scanning system radiation therapy is an effective palliative treatment for patients with multiple bone metastases. Toxicity can be tolerated.