检测肝脏特异性自身抗体对于认识肝炎或慢性肝病的自身免疫现象具有重要意义。本文作者使用改良的Hopf等间接荧光法,检测各型肝炎及中毒性肝损害共163例的肝细胞膜抗体(LMA)。健康对照42例,检测结果表明:慢活肝LMA的检出率(71.1％)明显高于急肝(24.2％)和慢迁肝(25％)。同时IMA的检出率 Detection of liver-specific autoantibodies is important for recognizing the autoimmune phenomenon of hepatitis or chronic liver disease. The authors used a modified Hopf indirect fluorescence method to detect a total of 163 cases of liver cell membrane antibody (LMA) in patients with hepatitis and toxic liver damage. Forty-two healthy controls showed that the detection rate of LMA was 71.1% in chronic active liver disease, which was significantly higher than that in acute liver disease (24.2%) and slow-moving liver disease (25%). Meanwhile, the detection rate of IMA