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双膦酸盐药物(BPs)是一种人工合成的化合物,主要作用是抑制破骨细胞的活性。随着该药广泛用于预防和治疗恶性肿瘤骨转移,大量相关文献报道其还具有抗肿瘤直接和间接作用,目前临床已将其作为抗癌药物的辅助药物进行使用。
Bisphosphonates (BPs) are synthetic compounds that function primarily to inhibit osteoclast activity. As the drug is widely used in the prevention and treatment of bone metastases of malignant tumors, a large number of relevant literature reports that it also has direct and indirect anti-tumor effects and has been used clinically as an adjunct to anticancer drugs.