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长期以来人们已认识到不稳定型心绞痛(unstable angina,usA)病人具有严重的不良后果,即心肌梗塞或猝死,症状顽固需行心肌血管再通术。对住院 USA 病人进行连续心电监护时证实:在发生 ST 段压低时80～90%的病人不伴有任何胸痛,而且许多研究表明无症状心肌缺血使这些病人的预后恶化。根据 cohn 的研究,硝酸盐类或钙拮抗剂对不伴有心肌工作负荷增加的无症状性心肌缺血发作提供了最好的疗法。虽然钙桔抗剂对解除 USA 病人的症状十分有用,但对无症状性心肌缺血疗效有限。有关静脉输注钙拮
It has long been recognized that patients with unstable angina (usA) have serious adverse consequences, such as myocardial infarction or sudden death, and cardioversion requiring recanalization. Continuous in-hospital ECG monitoring of hospitalized USA patients confirms that 80 to 90% of patients with ST-segment depression are not associated with any chest pain and many studies have shown that asymptomatic myocardial ischemia worsens the prognosis of these patients. According to cohn’s research, nitrates or calcium antagonists provide the best treatment for asymptomatic myocardial ischemia without increased myocardial workload. Although calcium citrate is very useful in relieving the symptoms of USA patients, it has limited efficacy in asymptomatic myocardial ischemia. About intravenous calcium antagonist