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5/6肾部分切除后,残余肾脏将发生一系列代偿性改变,其中肾小球肥大与肾小球硬化、肾功能不全进展的关系十分密切,本文初步观察了5/6肾切除大鼠的肾脏病理改变以及虫草对肾切除后肾脏病理改变的治疗作用。 实验动物用Wistar大鼠,手术切除5/6部分肾脏制备慢性肾功能不全模型。术后1周分为两组:(1)虫草治疗组,共6只大鼠,每日用虫草水煎剂(0.5g/ml)1.0ml灌胃1
5/6 partial nephrectomy, the residual kidney will occur a series of compensatory changes, including glomerular hypertrophy and glomerular sclerosis, renal insufficiency, the progress of the relationship is very close, the paper initially observed 5/6 nephrectomized rats Of renal pathological changes and Cordyceps after nephrectomy renal pathological changes in the treatment. Experimental Wistar rats were used to excise 5/6 part of the kidneys to prepare chronic renal insufficiency model. One week after the operation, the rats were divided into two groups: (1) Cordyceps treatment group, a total of 6 rats, intragastrically with 1.0ml of Cordyceps decoction (0.5g / ml)