用多克隆或单克隆抗体的双标记免疫荧光技术已经发现,正常人小肠粘膜中存在着不同亚群的淋巴细胞。据报道这些淋巴细胞均能与抗T细胞抗体反应,多数为HuTLA~+,OKT8~+。固有层中的HuTLA~+细胞则多为OKT8~-。为作进一步研究,作者采用了单克隆抗体的免疫荧光技术,以正常人及腹部疾病患者的小肠组织切片为实验材料,检测并比较了各淋巴细胞亚群的分布。 Dual-labeled immunofluorescence with polyclonal or monoclonal antibodies has found that there are different subsets of lymphocytes in the normal human small intestine mucosa. It is reported that these lymphocytes can react with anti-T cell antibodies, the majority of HuTLA ~ +, OKT8 ~ +. The lamina propria HuTLA ~ + cells are mostly OKT8 ~ -. For further study, the authors used monoclonal antibody immunofluorescence technology to normal and abdominal disease in patients with intestinal tissue sections as the experimental material, detection and comparison of the distribution of each lymphocyte subsets.