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分析69例妊娠胆淤(ICP)病例,进一步探讨治疗及处理。26例为治疗组、另43例为对照组。治疗组为28～37周妊娠患者,在原保胎保肝基础上,加用地塞米松口服,1.5毫克,日三次,7天为一疗程,经1～2个疗程后,治疗组全部病例搔痒症状明显改善;黄疸减退,甚至消失;肝功能好转或恢复正常。与对照组比较有显著差异(P<0.05),并由此使孕周以延长(平均延长12.3天),收到满意效果。在治疗期间未发现对母婴有毒副反应,故认为地塞米松是 ICP可选择的有效药物。
Analysis of 69 cases of pregnancy cholestasis (ICP), to further explore the treatment and treatment. 26 cases were treated group, the other 43 cases were control group. The treatment group was 28- to 37-week-old pregnant women. On the basis of the original unhealthy embryo and liver protection, dexamethasone plus 1.5 mg three times a day for one course of treatment was given. After 1 to 2 courses of treatment, all cases of itching in the treatment group Significant improvement; jaundice decreased, or even disappear; liver function improved or returned to normal. Compared with the control group, there was a significant difference (P <0.05), and thus prolonged gestational age (an average of 12.3 days), and received satisfactory results. Dexamethasone was considered to be an effective ICP-selective drug when no toxic or side effects were reported during treatment.