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目的观察替硝唑泡腾片联合替勃龙片(利维爱)治疗老年性阴道炎的临床效果。方法选取2012年5月—2013年5月我院收治的老年性阴道炎患者80例,采用随机数字表法将其分为对照组和观察组,各40例。对照组采用替硝唑泡腾片治疗,观察组在对照组基础上加用利维爱治疗。比较两组治疗前后阴道炎症评分、阴道脱落细胞成熟指数(MV)、阴道健康状况评分、雌二醇(E2)、促卵泡生成素(FSH)水平、子宫内膜厚度。结果治疗前两组患者MV、阴道健康状况评分、阴道炎症评分、子宫内膜厚度、E2、FSH水平比较,差异均无统计学意义(P>0.05)。治疗后观察组MV、阴道健康状况评分、子宫内膜厚度、E2水平均高于对照组,阴道炎症评分、FSH均低于对照组(P<0.05)。结论替硝唑泡腾片联合利维爱治疗老年性阴道炎疗效佳,使用方便,不良反应少,值得临床推广应用。
Objective To observe the clinical effect of tinidazole effervescent tablets combined with tibolone tablets (Levi) in the treatment of senile vaginitis. Methods 80 cases of senile vaginitis admitted in our hospital from May 2012 to May 2013 were randomly divided into control group and observation group with 40 cases in each group. The control group was treated with tinidazole effervescent tablets. The observation group was treated with leviotherapy on the basis of the control group. Vaginal inflammatory score, vaginal exfoliated cell maturation index (MV), vaginal health score, estradiol (E2), follicle stimulating hormone (FSH) level and endometrial thickness were compared between the two groups before and after treatment. Results There were no significant differences in MV, vaginal health score, vaginal inflammation score, endometrial thickness, E2 and FSH levels between the two groups before treatment (P> 0.05). After treatment, MV, vaginal health score, endometrial thickness and E2 level in the observation group were higher than those in the control group. Vaginal inflammation score and FSH were lower in the observation group than those in the control group (P <0.05). Conclusion Tinidazole effervescent tablets combined with Levi love treatment of senile vaginitis good effect, easy to use, less adverse reactions, it is worthy of clinical application.