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目的:了解阴道炎患者阴道分泌物病原学分布及药敏情况。方法:选择2011年1月～2012年12月68例阴道炎患者,对患者的阴道分泌物进行病原学检测,并对检出的主要病原体进行药敏实验。结果:68例阴道炎患者中,假丝酵母菌、滴虫、细菌阳性者共45例,阳性检出率66.2%。68例阴道炎患者标本中,共检出病原体218株,其中最多的为白色假丝酵母菌。两种真菌对伏立康唑、两性霉素B、伊曲康唑、氟康唑、5-氟胞嘧啶等药物均比较敏感;单纯UU型支原体感染对交沙霉素、强力霉素、司帕沙星均比较敏感,UU和MH混合型的菌株对阿奇霉素、环丙霉素、克拉霉素、多红霉素的耐药性都比较强;粪肠球菌对复方新诺明、克林霉素、四环素有着极强的耐药性,无乳链球菌对红霉素、四环素有着极强的耐药性,大肠埃希菌对氨苄西林、复方新诺明以及一些头孢类药物有一定耐药性,肺炎克雷伯菌对氨苄西林的耐药性较强。结论:不同的致病菌对于不同的药物有着不同的敏感性,在治疗女性阴道炎时,应充分考虑到病原体的耐药性,做到对因治疗,合理用药。
OBJECTIVE: To understand the etiological distribution and drug sensitivity of vaginal secretions in patients with vaginitis. Methods: Sixty-eight patients with vaginitis were selected from January 2011 to December 2012. The vaginal secretions of the patients were tested for pathogenicity and the main pathogens detected were tested for susceptibility. Results: In 68 cases of vaginitis patients, Candida, trichomoniasis, bacteria were positive in a total of 45 cases, the positive detection rate was 66.2%. 68 samples of vaginitis patients, a total of 218 pathogens were detected, the largest of which is Candida albicans. Both fungi were more sensitive to voriconazole, amphotericin B, itraconazole, fluconazole, 5-fluorocytosine and other drugs; simple UU mycoplasma infection josamycin, doxycycline, sparfloxacin Were more sensitive, UU and MH mixed strains of azithromycin, cyclosporine, clarithromycin, erythromycin resistance are relatively strong; Enterococcus faecalis cotrimoxazole, clindamycin, tetracycline Has a strong resistance to Streptococcus agalactiae on erythromycin, tetracycline has a strong resistance to Escherichia coli ampicillin, cotrimoxazole and some cephalosporins have some resistance, pneumonia Klebsiella was more resistant to ampicillin. Conclusion: Different pathogenic bacteria have different sensitivities to different drugs. In the treatment of vaginitis in women, the drug resistance of pathogens should be fully taken into account, so that due to treatment, rational use of drugs should be taken.