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D、L—乳酸立体共聚物和D、L—乳酸与乙醇酸共聚物常用于控制药物释放的生物可吸收载体,某些作者创立了化学栓塞,用含抗分裂药物进行抗肿瘤治疗,载体慢慢消失。而本文作者运用溶解蒸发法制备聚(D、L丙交酯/甘油化物)微球,考察体内外降解及研究β-射线对该微球的稳定有何影响。用聚(D、L乳酸)立体共聚物和(D、L—乳—10—乙醇酸)共聚物与D、L丙交酯和甘油化物开环聚合制成聚(d—羟基酸)微球,直径为40～200μm,经γ—射线
D, L-lactic acid copolymers and D, L-lactic acid and glycolic acid copolymers are commonly used to control bioavailability of drug-released carriers. Some authors have established chemoembolization with anti-tumor drugs containing anti-schizophrenic drugs. Slower carriers Slowly disappear. However, the authors prepared the poly (D, L-lactide / glyceridate) microspheres by dissolving evaporation method and investigated the in vitro and in vivo degradation and the effect of β-rays on the stability of the microspheres. Poly (d-hydroxy acid) microspheres were prepared by ring-opening polymerization of poly (D, L lactic acid) stereopolymers and copolymers of (D, L-lactide-10-glycolic acid) with D, L lactide and glycerol , Diameter of 40 ~ 200μm, the γ-ray