1　临床资料　患者女性 ,63岁 ,因多关节对称性肿痛 2 2年 ,发热 3个月余入院。患者于 1961年确诊甲状腺功能亢进症(甲亢 ) ,甲基硫氧嘧啶口服半年后痊愈。 1975年 10月 ,出现眼睑下垂 ,吞咽困难 ,言语含糊 ,双下肢无力 ,晨轻暮重 ,烟碱型乙酰胆碱受体 ( n Ach R)抗体升高 ,新 1 Clinical data Patients Female, 63 years old, due to multi-joint symmetrical swelling and pain 2 2 years, fever more than 3 months admitted to hospital. Patients were diagnosed with hyperthyroidism (hyperthyroidism) in 1961, and methylthiouracil was cured after oral administration for six months. October 1975, there eyelid ptosis, swallowing difficulties, vague language, weakness of both lower extremities, morning and evening heavy, nicotinic acetylcholine receptor (nAch R) antibody increased, the new