论文部分内容阅读
目的:观察盐酸贝那普利联合具有益气、养阴、活血作用的中药治疗糖尿病肾病(DN)的临床疗效。方法:将60例病人随机分为两组,治疗组30例,服用盐酸贝那普利及具有益气、养阴、活血作用的中药生地黄12 g,黄芪30 g,苍术12 g,玄参12 g,丹参15 g,葛根12 g,川芎12 g,当归12 g,麦冬12 g,山药15 g,甘草6 g,水煎服,每日1剂,早晚饭后分服。治疗;对照组30例,服用盐酸贝那普利自2.5 mg逐渐增至能耐受的最大剂量治疗。结果:治疗组总疗效93.3%明显优于对照组70%(P<0.05),治疗组在改善患者症状、体征,降低24 h尿蛋白定量方面经统计学处理明显优于对照组(P<0.05)。结论:盐酸贝那普利联合具有益气、养阴、活血作用的中药治疗DN的临床疗效优于单用盐酸贝那普利。
Objective: To observe the clinical efficacy of benazepril hydrochloride in combination with traditional Chinese medicine for treating diabetic nephropathy (DN) with the effects of supplementing qi, nourishing yin and promoting blood circulation. Methods: Sixty patients were randomly divided into two groups. The treatment group consisted of 30 patients taking benazepril hydrochloride and traditional Chinese medicine Rehmanniae Decoction 12g, astragalus root 30g, herb 12g, figwort 12 g, Salvia 15 g, Pueraria 12 g, Chuanxiong 12 g, Angelica 12 g, Ophiopogon 12 g, yam 15 g, licorice 6 g, Shuijianbi day 1, morning and evening meal after serving. Treatment; control group of 30 patients, taking benazepril hydrochloride gradually increased from 2.5 mg to tolerate the maximum dose of treatment. Results: The total effective rate of the treatment group was 93.3%, which was significantly better than that of the control group (P <0.05). The treatment group was significantly better than the control group (P <0.05) in improving symptoms and signs of the patients and reducing the proteinuria of 24- ). Conclusion: The combination of benazepril hydrochloride and traditional Chinese medicine with Qi, Yin, activating blood circulation is superior to benazepril alone in the treatment of DN.