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常规化疗可以使慢性粒细胞白血病(CML)得到缓解,然而直到目前为止,化疗并不能预防或延缓急变的发生与延长患者的寿命。因此许多学者企图应用骨髓移植(BMT)来治疗CML。在进展期或急变期进行同基因BMT,由于早期感染、间质性肺炎、不能根除白血病和不完全植活,其结果已使人失望。一组14例病人的研究中(10例于急变期、3例于进展期、1例为化疗后继发的再生障碍),
Conventional chemotherapy can relieve chronic myelogenous leukemia (CML), but so far, chemotherapy can not prevent or delay the occurrence of rapid changes and extend the life of patients. Therefore, many scholars have attempted to use bone marrow transplantation (BMT) to treat CML. Syngeneic BMT is performed in advanced or blast crisis. The results have been disappointing due to early infection, interstitial pneumonia, inability to eradicate leukemia and incomplete engraftment. A group of 14 patients studied (10 in the blast phase, 3 in the advanced phase, and 1 in the secondary relapse after chemotherapy).